國立陽明交通大學生物科技學系
Department of Biological Science and Technology, National Yang Ming Chiao Tung University
新竹市博愛街75號賢齊樓537室(辦公室),540室(實驗室)
R537 (O), R540 (L), Bio-ICT building, 75, Po-Ai Street, Hsinchu, Taiwan, 30068, ROC.
電話: 03-5731633 (辦公室); 03-5712121 ext 56959 (實驗室)
TEL: +886-3-5731633 (Office); +886-3-5712121 ext 56959 (Lab)
E-mail: ccchang01@nycu.edu.tw
TeTe
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Sonodynamic therapy
ROS-generating alginate-coated gold nanorods as biocompatible nanosonosensitisers for effective sonodynamic therapy of cancer
Ultrasonics Sonochemistry (2023) 96, 106437 (IF 9.336, Rank 1/32, Top 3%, Acoustic)
2021 Future Tech Award
Virus sensing and anti-infection molecules screening biosensing platform development by palladium nano-thin-film electrochemical spectroscopy
Ni-DNA devices possesses memcapacitor and memristor properties
Chu H.L. et al., Exploration and Characterization of the Memcapacitor and Memristor Properties of Ni-DNA Nanowire Devices (2017) NPG Asia Materials9, e430. (SCI IF:10.481; Ranking 37/335, Materials Science, Multidisciplinary)
Single domain antibody development
Cheng T.-M. et al, Single domain antibody against carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) inhibits proliferation, migration, invasion and angiogenesis of pancreatic cancer cells, Eur. J. Cancer (2014) 50, 713-721. (IF: 9.162, Ranking 33/242, Oncology)
Drug delivery system development
Nano-particles can be used as nanocarriers to improve the delivery and efficacy of antimetastatic agents is less explored when compared to cytotoxic agents.
- Fong S.S. et al., Chitosan-coated-PLGA nanoparticles enhance the antitumor and antimigration activity of Stattic – a STAT3 dimerization blocker, (2022) International Journal of Nanomedicine 17, 137-150 (IF 7.033, Rank 32/279, Top 10%, Pharmacology & Pharmacy, Citation 4)
Native LDL can be used as anti-cancer drug delivery system
1. Chu H.-L. et al., Synthesis of apolipoprotein B lipoparticles to deliver hydrophobic/amphiphilic materials. ACS Appl. Mater. Interfaces. (2013) 5, 7509-7516. ( IF: 10.383, Ranking 49/345, Materials Science, Multidisciplinary)
2. Yang C.-L., et al., Local ablation of gastric cancer by reconstituted apolipoprotein B lipoparticles carrying epigenetic drugs (2021) Nanomedicine: Nanotechnology, Biology and Medicine, 37, 102450 (IF=6.458, Rank=28/140, Top 20 %, Medicine, Research & experimental)
Single EV71 virus detection platform development
Single EV71 virus detection platform development/ 腸病毒單一分子感測平台開發 (Nanotechnology, 2013; IF: 3.440)